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quinupristin/dalfopristin will raise the amount or effect of sparsentan by affecting hepatic/intestinal enzyme CYP3A4 metabolism.quinupristin/dalfopristin will improve the level or outcome of donepezil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Not known.It might come about 2 months or maybe more after you